Route

Chicago to San Francisco by train

3 rail vacations run between Chicago and San Francisco, from 2 operators, 5 to 16 days, from $795 per person. Trips running the reverse direction are included; the itinerary pages show exact routings.

Amtrak Vacations

Grand Northern Rail Experience

Independent Amtrak roundtrip from Chicago to Seattle and San Francisco

12 daysfrom $2,059

42% rail

Amtrak Vacations

Rails Across America The Beautiful

16-day rail journey from Chicago to San Francisco on the California Zephyr

16 daysfrom $2,439

31% rail

Vacations By Rail

California Zephyr Experience

5 daysfrom $795